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2-Me-DET, or 2-methyl-DET, also known as 2-methyl-N,N-diethyltryptamine, is a psychedelic drug of the tryptamine family.^[1] It is the 2-methyl derivative of diethyltryptamine (DET).^[1] The drug is taken orally.^[1]

In his book TiHKAL (Tryptamines I Have Known and Loved), Alexander Shulgin lists 2-Me-DET’s dose as 80 to 120 mg orally and its duration as 6 to 8 hours.^[1] The effects of 2-Me-DET have been reported to include a vague unreal feeling, clouding and slowing of thoughts, DiPT-like sound distortion including higher pitches of music sounding muffled and tones shifting to a lower frequency, and stomach ache.^[1]

The chemical synthesis of 2-Me-DET has been described.^[1]

Analogues of 2-Me-DET include 2-methyltryptamine (2-MT; 2-Me-T), 2-methyl-DMT (2-Me-DMT; 2,N,N-TMT), 2-methyl-5-MeO-DMT (5-MeO-2,N,N-TMT), and 2-methyl-AMT (2-Me-AMT; 2,α-DMT).^[1]

2-Me-DET was first described in the scientific literature by R. B. Barlow and I. Khan in 1959.^[2] Subsequently, it was described in greater detail by Alexander Shulgin in his 1997 book TiHKAL (Tryptamines I Have Known and Loved).^[1]

• Substituted tryptamine

• 2-Methyl-DET – Isomer Design
• 2-Me-DET – TiHKAL – Erowid
• 2-Me-DET – TiHKAL – Isomer Design