MDMP, also known as 3,4-methylenedioxy-N-methylphentermine or as α-methyl-MDMA, is a lesser-known psychoactive drug of the phenethylamine, amphetamine, and MDx families.[1]
Use and effects
In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists MDMP’s minimum dose as 110 mg orally and its duration as “perhaps 6 hours”.[1] MDMP produces few to no effects, and is slightly similar to MDMA.[1]
Pharmacology
Pharmacodynamics
MDMP failed to act as a serotonin releasing agent in rat brain synaptosomes in vitro.[2][3][4]
Chemistry
Synthesis
The chemical synthesis of MDMP has been described.[1]
Society and culture
Legal status
United Kingdom
This substance is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act.[5]
See also
References
- ^ a b c d e f Shulgin A, Shulgin A (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. MDMP entry
- ^ Nichols DE, Oberlender R (1989). “Structure-activity relationships of MDMA-like substances” (PDF). NIDA Research Monograph. 94: 1–29. PMID 2575223. Archived from the original (PDF) on May 11, 2023.
- ^ Nichols DF, Oberlender R (1990). “Structure-Activity Relationships of MDMA and Related Compounds: A New Class of Psychoactive Agents?”. Ecstasy: The Clinical, Pharmacological and Neurotoxicological Effects of the Drug MDMA. Topics in the Neurosciences. Vol. 9. Boston, MA: Springer US. pp. 105–131. doi:10.1007/978-1-4613-1485-1_7. ISBN 978-1-4612-8799-5. PMID 1979214. Retrieved 19 November 2025.
- ^ Nichols DE, Lloyd DH, Hoffman AJ, Nichols MB, Yim GK (May 1982). “Effects of certain hallucinogenic amphetamine analogues on the release of [3H]serotonin from rat brain synaptosomes”. Journal of Medicinal Chemistry. 25 (5): 530–535. doi:10.1021/jm00347a010. PMID 7086839.
- ^ “UK Misuse of Drugs act 2001 Amendment summary”. Isomer Design. Archived from the original on 22 October 2017. Retrieved 12 March 2014.