Asian Highway 16 (AH16) is a road in the Asian Highway Network running 1,031 kilometres (641 mi) from Tak, Thailand to Đông Hà, Vietnam connecting AH1 and AH2 to AH1 after AH1 takes a turn from south to North after crossing Cambodia. The route is as follows:
Thailand
Route 12: Tak (
AH1
AH2) – Phitsanulok (
AH13)- Khon Kaen (
AH12) – Somdet – Mukdahan
Route 212: Mukdahan – Bang Sai Yai
Route 239: Second Thai–Lao Friendship Bridge
Laos
Route 9W: Savannakhet – Xeno
Route 13: Xeno (concurrent with 
AH11 for 3 km)
Route 9E: Xeno – Xépôn – Dansavan
Vietnam
| Across the whole continent |  | |
|---|---|---|
| Southeast Asia | ||
| East Asia, Northeast Asia and Southeast Asia | ||
| South Asia | ||
| North Asia, Central Asia and Southwest Asia | ||