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Alpha,Beta-D, or α,β-D, also known as α,β-dideuteromescaline, is a psychedelic drug of the phenethylamine and scaline families related to mescaline.[1] It is the deuterated isotopologue of mescaline in which one hydrogen atom at the α position and one hydrogen atom at the β position have been replaced with the deuterium isotopes.[1]

According to Daniel Trachsel in his book Phenethylamine: von der Struktur zur Funktion (Phenethylamines: From Structure to Function), α,β-D at a dose of 250 mg orally produces effects comparable to an equivalent dose of mescaline, but had a somewhat more rapid onset.[1] This information was based on anonymous personal communication to Trachsel in 2009.[1] The similar potency of α,β-D to mescaline is in contrast to the case of α-D (α,α-dideuteromescaline), which was reported to be roughly one-third more potent than mescaline based on limited testing.[1]

The chemical synthesis of α,β-D has been described.[1] It has four possible theoretical stereoisomers.[1]

α,β-D was first described in the scientific literature by Trachsel in his book in 2013.[1]

See also

References

  1. ^ a b c d e f g h i j k Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine: von der Struktur zur Funktion [Phenethylamines: From Structure to Function]. Nachtschatten-Science (in German) (1 ed.). Solothurn: Nachtschatten-Verlag. ISBN 978-3-03788-700-4. OCLC 858805226. Archived from the original on 21 August 2025.