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Bendazac (or bendazolic acid) is a nonsteroidal anti-inflammatory drug (NSAID) used for joint and muscular pain.[1]

Synthesis

Principal action is inhibition of protein denaturation.

Bendazac synthesis: BE 699226 ; G. Palazzo, U.S. patent 3,470,194 (1967, 1969 both to Francesco Angelini).

Use of chloroacetamide in the alkylation step, followed by acid hydrolysis produces bendazac (instead of benzydamine).

See also

References

  1. ^ Balfour JA, Clissold SP (April 1990). “Bendazac lysine. A review of its pharmacological properties and therapeutic potential in the management of cataracts”. Drugs. 39 (4): 575–96. doi:10.2165/00003495-199039040-00007. PMID 2190795. S2CID 46956362.