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Cold-inducible RNA-binding protein is a protein that in humans is encoded by the CIRBP gene.[5][6][7] The cold inducible RNA-binding protein CIRBP plays a critical role in controlling the cellular response upon confronting a variety of cellular stresses, including short wavelength ultraviolet light, hypoxia, and hypothermia. It is thought to be involved in DNA repair.[8]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000099622Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045193Ensembl, May 2017
  3. ^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nishiyama H, Higashitsuji H, Yokoi H, Itoh K, Danno S, Matsuda T, et al. (December 1997). “Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene”. Gene. 204 (1–2): 115–120. doi:10.1016/S0378-1119(97)00530-1. PMID 9434172.
  6. ^ Nishiyama H, Itoh K, Kaneko Y, Kishishita M, Yoshida O, Fujita J (May 1997). “A glycine-rich RNA-binding protein mediating cold-inducible suppression of mammalian cell growth”. The Journal of Cell Biology. 137 (4): 899–908. doi:10.1083/jcb.137.4.899. PMC 2139845. PMID 9151692.
  7. ^ “Entrez Gene: CIRBP cold inducible RNA binding protein”.
  8. ^ Firsanov D, Zacher M, Tian X, Sformo TL, Zhao Y, Tombline G, et al. (November 2024). “DNA repair and anti-cancer mechanisms in the long-lived bowhead whale”. bioRxiv 10.1101/2023.05.07.539748.

Further reading