Cuminaldehyde (4-isopropylbenzaldehyde) is a natural organic compound with the molecular formula C10H12O. It is a benzaldehyde with an isopropyl group substituted in the 4-position.
Uses and occurrence
Cuminaldehyde is responsible for the characteristic aroma of cumin seed. It has an intense aroma described as “spicy, cumin, green, herbal”.[2] Cuminaldehyde is a precursor to another commercially important fragrance, cyclamen aldehyde.[3]
Cuminaldehyde has been investigated for inhibition of the fibrillation of alpha-synuclein,[4]
Cuminaldehyde can be prepared synthetically by the reduction of 4-isopropylbenzoyl chloride or by the formylation of cumene.
References
- ^ Merck Index, 11th Edition, 2623
- ^ “cuminaldehyde”. Scents and Flavors. Scents and Flavors. Retrieved 29 March 2026.
- ^ Panten, Johannes; Surburg, Horst (2016). “Flavors and Fragrances, 3. Aromatic and Heterocyclic Compounds”. Ullmann’s Encyclopedia of Industrial Chemistry. pp. 1–45. doi:10.1002/14356007.t11_t02. ISBN 978-3-527-30673-2.
- ^ Morshedi D; Aliakbari F; Tayaranian-Marvian, Fassihi; Pan-Montojo, Pérez-Sánchez (Sep 2015). “Cuminaldehyde as the Major Component of Cuminum cyminum, a Natural Aldehyde with Inhibitory Effect on Alpha-Synuclein Fibrillation and Cytotoxicity”. Journal of Food Science. 80 (10): H2336–H2345. doi:10.1111/1750-3841.13016. PMID 26351865.