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Pentethylcyclanone is an antitussive medication.[1]

Synthesis

Pentethylcyclanone can be prepared by alkylation of the anion of the self-condensation product of cyclopentanone with N-(2-chloroethyl)-morpholine.[2][1]

Cyclexanone synthesis

References

  1. ^ a b Dutta S, Bhat NS (December 2021). “Catalytic Transformation of Biomass-Derived Furfurals to Cyclopentanones and Their Derivatives: A Review”. ACS Omega. 6 (51): 35145–35172. doi:10.1021/acsomega.1c05861. PMC 8717399. PMID 34984249.
  2. ^ DE 1059901, Ueberwasser H, ”Verfahren zur Herstellung von substituierten 2-Amino-alkylcycloalkanonen bzw, ihren Salzen [Process for the preparation of substituted 2-amino-alkylcycloalkanones or their salts]”, published 1959-06-25, assigned to Ciba AG