Felbinac (INN, or biphenylylacetic acid) is a topical medicine,[1] belonging to the family of medicines known as nonsteroidal anti-inflammatory drugs (NSAIDs) of the arylacetic acid (not arylpropionic acid) class, which is used to treat muscle inflammation and arthritis.[2] It is an active metabolite of fenbufen.[3]
Related compounds
The α-methyl acid of felbinac is called biprofen and is used to prepare bifepramide. The α-ethyl acid is called xenbucin which is used to make xenthiorate.
See also
References
- ^ The Merck Index, 12th Edition. 3989
- ^ Description of Felbinac on Tiscali [1]
- ^ Kohler C, Tolman E, Wooding W, Ellenbogen L (1980). “A review of the effects of fenbufen and a metabolite, biphenylacetic acid, on platelet biochemistry and function”. Arzneimittelforschung. 30 (4A): 702–707. PMID 6254545.
| pyrazolones / pyrazolidines | |
|---|---|
| salicylates | |
| acetic acid derivatives and related substances | |
| oxicams | |
| propionic acid derivatives (profens) |
|
| n-arylanthranilic acids (fenamates) | |
| COX-2 inhibitors (coxibs) | |
| other | |
| NSAID combinations | |
Key: underline indicates initially developed first-in-class compound of specific group; #WHO-Essential Medicines; †withdrawn drugs; ‡veterinary use. | |
