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Haematin (also known as hematin, ferriheme, hematosin, hydroxyhemin, oxyheme, phenodin, or oxyhemochromogen) is a dark bluish or brownish pigment containing iron in the ferric state, obtained by the oxidation of haem.

Haematin inhibits the synthesis of porphyrin (by repressing ALAS1 synthesis),^[1] and stimulates the synthesis of globin. For this reason, it is used in the treatment of porphyrias.^[1]

It is a component of cytochromes and peroxidases. Haematin derived synthetically from hemin is used as a reagent.

References

^ ^a ^b Rodwell, Victor W. (2018). Harper’s Illustrated Biochemistry (31st ed.). McGraw-Hill Education. p. 311. ISBN 978-1-25-983794-4.

[rdp-we-cite_note-:0-1] Rodwell, Victor W. (2018). Harper’s Illustrated Biochemistry (31st ed.). McGraw-Hill Education. p. 311. ISBN 978-1-25-983794-4.

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