Indanols are a class of organic compounds, some of which are useful in medicine or industry. They are hydroxy derivatives of the parent compound called indane (also known as indan).
Isomers
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1-indanol (racemic), m.p. 54.8; R enantiomer, m.p. 67-68°C
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2-indanol, m.p. 68-69 °C
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4-indanol, m.p. 42 °C
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5-indanol, m.p. 58 °C
Five isomers are possible, two of which are phenols (4- and 5-indanols). Three isomers feature hydroxyl group on the five-membered ring, including an enantiomeric pair of 1-indanol. 1-Indanol can be produced by reduction of 1-indanone.[1] 5-indanol can be prepared by sulfonation of indane, following by base cleavage of the indane-5-sulfonate.[2]
References
- ^ “(S)-Tetrahydro-1-Methyl-3,3-Diphenyl-1H,3H-Pyrrolo-[1,2-c][1,3,2]Oxazaborole-Borane Complex”. Organic Syntheses. 74: 50. 1997. doi:10.15227/orgsyn.074.0050.
- ^ Fiege, Helmut; Voges, Heinz-Werner; Hamamoto, Toshikazu; Umemura, Sumio; Iwata, Tadao; Miki, Hisaya; Fujita, Yasuhiro; Buysch, Hans-Josef; Garbe, Dorothea; Paulus, Wilfried (2000). “Phenol Derivatives”. Ullmann’s Encyclopedia of Industrial Chemistry. doi:10.1002/14356007.a19_313. ISBN 978-3-527-30385-4.