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Innovation Cluster Ranking is an annual ranking of the world’s largest innovation clusters published as part of the Global Innovation Index (GII) by the World Intellectual Property Organization (WIPO). The ranking identifies geographically concentrated areas of innovation activity, using data on international patent filings, scientific publications and, since 2025, venture-capital deal locations. Unlike rankings based on administrative units, the cluster ranking uses a bottom-up geocoding method and may therefore define clusters that span several municipalities, subnational regions or countries.[1]

The 2025 edition ranked Shenzhen–Hong Kong–Guangzhou first, followed by Tokyo–Yokohama, San Jose–San Francisco, Beijing and Seoul.[2] The top 100 clusters together accounted for about 70 percent of global Patent Cooperation Treaty filings and venture-capital deal activity, and around half of all scientific publications covered by the ranking.[3]

History

The Global Innovation Index began work on identifying science and technology clusters by means of a bottom-up approach in 2016.[1] A first top-100 cluster ranking was published in the 2017 edition of the GII in a special section titled Identifying and Ranking the World’s Largest Clusters of Inventive Activity. That early ranking focused on inventive activity and used patent data, particularly international patent applications filed under the Patent Cooperation Treaty.[4]

The cluster ranking was later developed into a regular component of the Global Innovation Index. By the early 2020s, the methodology combined patent data with scientific publication data in order to capture both inventive and research activity.[5] Since 2020, WIPO has also published an intensity ranking that adjusts innovation activity by estimated cluster population.[3]

In 2025, WIPO revised the ranking by adding venture-capital deal locations as a third indicator. WIPO Director General Daren Tang stated that adding venture-capital activity helped show which clusters were translating scientific research into economic results.[6][1] The revised methodology contributed to Shenzhen–Hong Kong–Guangzhou overtaking Tokyo–Yokohama as the top-ranked cluster in 2025, because the Chinese-Hong Kong cluster performed more strongly on venture-capital deal activity.[3]

Methodology

The Innovation Cluster Ranking is based on a geocoding and clustering process. In 2025, WIPO used three innovation metrics: the location of inventors listed in published patent applications, the location of authors listed in scientific articles, and the location of firms receiving venture-capital investment.[1]

Patent data are based on published applications filed under the Patent Cooperation Treaty. WIPO uses PCT applications because the system applies common procedural rules and uniform filing standards, reducing biases that could arise from comparing national patent systems. For the 2025 ranking, the patent data covered applications published between 2020 and 2024.[1]

Scientific publications are taken from the Science Citation Index Expanded of the Web of Science. The ranking focuses on science and technology fields and excludes publications from the social sciences and humanities, as well as non-original research items such as meeting abstracts and conference summaries. For the 2025 edition, the scientific publication data covered the years 2019 to 2023.[1]

The venture-capital component, introduced in 2025, uses PitchBook venture-capital data. WIPO counted VC transactions by the headquarters location of the company receiving investment, while excluding pure debt deals and most accelerator-program deals. The 2025 VC data set covered 66,755 locations and 236,046 deals from 2019 to 2023.[1]

Addresses are geocoded using ESRI’s ArcGIS World Geocoder and the GeoNames gazetteer. WIPO reported that, in 2025, 98.4 percent of inventor addresses, 99.7 percent of scientific author addresses and 97.1 percent of VC deals were geocoded at city level or better.[1] Cluster formation is based on the DBSCAN algorithm, using a radius of 15 kilometres and a density parameter of 4,500 inventor or author records. Venture-capital locations are not used to form the clusters initially; instead, they are assigned to already-defined cluster boundaries.[1]

The resulting clusters are ranked by counting patents, scientific articles and VC deals within each cluster, calculating each cluster’s global share for the three indicators and aggregating the three shares with equal weights. The 2025 procedure identified 237 clusters overall, from which the top 100 were published in the main ranking.[1]

Ranking

In the 2025 ranking, China had the largest number of top-100 clusters with 24, followed by the United States with 22 and Germany with seven. India and the United Kingdom each had four clusters in the top 100.[3]

Top 100 innovation clusters, 2025
Rank Cluster Economy or economies
1 ShenzhenHong KongGuangzhou China / Hong Kong
2 TokyoYokohama Japan
3 San JoseSan Francisco United States
4 Beijing China
5 Seoul South Korea
6 ShanghaiSuzhou China
7 New York City United States
8 London United Kingdom
9 BostonCambridge United States
10 Los Angeles United States
11 OsakaKobeKyoto Japan
12 Paris France
13 Hangzhou China
14 San Diego United States
15 Nanjing China
16 SingaporeJohor Bahru Singapore / Malaysia
17 WashingtonBaltimore United States
18 Wuhan China
19 Tel AvivJerusalem Israel
20 Seattle United States
21 Bengaluru India
22 AmsterdamRotterdam Netherlands
23 Philadelphia United States
24 Chengdu China
25 Daejeon South Korea
26 Delhi India
27 Munich Germany
28 Nagoya Japan
29 Xi’an China
30 Berlin Germany
31 Chicago United States
32 Stockholm Sweden
33 Toronto Canada
34 Qingdao China
35 Denver United States
36 Sydney Australia
37 Austin United States
38 Houston United States
39 Hefei China
40 Zürich  Switzerland
41 TaipeiHsinchu Taiwan
42 Copenhagen Denmark
43 Cologne Germany
44 Changsha China
45 Barcelona Spain
46 Mumbai India
47 Madrid Spain
48 Moscow Russia
49 São Paulo Brazil
50 Tianjin China
51 Minneapolis United States
52 Melbourne Australia
53 Raleigh United States
54 Stuttgart Germany
55 BrusselsAntwerp Belgium
56 Milan Italy
57 Chongqing China
58 Istanbul Turkey
59 Atlanta United States
60 Helsinki Finland
61 Dallas United States
62 Montréal Canada
63 Tehran Iran
64 Frankfurt am Main Germany
65 Eindhoven Netherlands
66 Vancouver Canada
67 Miami United States
68 Jinan China
69 Cambridge United Kingdom
70 Harbin China
71 Dublin Ireland
72 Changchun China
73 Portland United States
74 Vienna Austria
75 Shenyang China
76 Pittsburgh United States
77 Oxford United Kingdom
78 Phoenix United States
79 Mexico City Mexico
80 Zhengzhou China
81 Xiamen China
82 Rome Italy
83 Cairo Egypt
84 Chennai India
85 Oslo Norway
86 Kuala Lumpur Malaysia
87 HeidelbergMannheim Germany
88 Dalian China
89 Warsaw Poland
90 Lyon France
91 Hamburg Germany
92 Salt Lake City United States
93 Ningbo China
94 Manchester United Kingdom
95 Busan South Korea
96 Ann Arbor United States
97 Göteborg Sweden
98 MacauZhuhai China
99 Ningde China
100 Zhenjiang China

[3]

Reception

The ranking has been cited in international and regional media coverage of technology policy, national competitiveness and innovation geography.[7][8][9][10][11]

The rise of Shenzhen–Hong Kong–Guangzhou to first place received particular attention in Chinese and Hong Kong media. Xinhua, in a report republished by the English-language website of the State Council of China, described the result as the first time the cluster had overtaken Tokyo–Yokohama and linked the ranking to the development of the Guangdong–Hong Kong–Macao Greater Bay Area.[12] Time Out Hong Kong similarly reported that the 2025 ranking had recognized Shenzhen–Hong Kong–Guangzhou as the world’s leading innovation hub after WIPO added venture-capital activity to the methodology.[13]

See also

References

  1. ^ a b c d e f g h i j “Appendix IV – Global Innovation Index innovation cluster methodology”. Global Innovation Index 2025. World Intellectual Property Organization. Retrieved 13 May 2026.
  2. ^ “Innovation Cluster Ranking 2025”. Global Innovation Index. World Intellectual Property Organization. Retrieved 13 May 2026.
  3. ^ a b c d e 2025 GII Ranking of World’s Top 100 Innovation Clusters (PDF) (Report). World Intellectual Property Organization. 2025. Retrieved 13 May 2026.
  4. ^ Identifying and Ranking the World’s Largest Clusters of Inventive Activity (PDF) (Report). Cornell University, INSEAD and World Intellectual Property Organization. 2017. Retrieved 13 May 2026.
  5. ^ Global Innovation Index 2024: Appendix IV – Global Innovation Index science and technology cluster methodology (PDF) (Report). World Intellectual Property Organization. 2024. Retrieved 13 May 2026.
  6. ^ “Venture Capital Metric Reshapes WIPO’s Global Innovation Cluster Rankings”. Global Innovation Index. World Intellectual Property Organization. 1 September 2025. Retrieved 13 May 2026.
  7. ^ “China replaces Germany in top 10 of UN’s most innovative nations”. Reuters. 16 September 2025. Retrieved 13 May 2026.
  8. ^ “Deutschland fliegt aus den Top 10 der innovativsten Länder”. Die Welt. dpa. 18 September 2025. Retrieved 13 May 2026.
  9. ^ “Chinese cluster now world’s top innovation hotspot: UN”. RFI. 2025-09-01. Retrieved 2026-05-13.
  10. ^ “EISMEA – Global Innovation Index S&T Cluster Ranking: Chennai, India Sees 7.8% Growth”. ec.europa.eu. Retrieved 2026-05-13.
  11. ^ “China has world’s largest number of top 100 science, technology clusters”. www.ecns.cn. Retrieved 2026-05-13.
  12. ^ “Shenzhen-HK-Guangzhou innovation cluster tops global ranking for first time”. english.www.gov.cn. Xinhua. 2 September 2025. Retrieved 13 May 2026.
  13. ^ Pang, Genevieve (13 September 2025). “Shenzhen–Hong Kong–Guangzhou is recognised as the world’s top innovation hub”. Time Out Hong Kong. Retrieved 13 May 2026.