Methadone intermediate (pre-methadone, methadone nitrile, dimethylaminodiphenylbutanonitrile) is a methadone precursor scheduled by UN Single Convention on Narcotic Drugs. It is a Schedule II Narcotic controlled substance in the United States and has an ACSCN of 9254. The 2014 annual manufacturing quota was 32 875 kilos.[3] It is listed as a Schedule I drug in Canada,[4] but is only significant as a precursor for methadone, as it does not have analgesic activity in its own right, though it does show some atropine-like activity.[5]
See also
- Moramide intermediate
- Pethidine intermediate A
- Pethidine intermediate B (norpethidine)
- Pethidine intermediate C (pethidinic acid)
References
- ^ “STANDARD FOR THE UNIFORM SCHEDULING OF MEDICINES AND POISONS”. Federal Register of Legislation. October 2020. Archived from the original on 2021-01-25. Retrieved 2021-08-15.
- ^ Anvisa (2023-03-31). “RDC Nº 784 – Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial” [Collegiate Board Resolution No. 784 – Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
- ^ “Quotas – Conversion Factors for Controlled Substances”. Archived from the original on 2016-03-02. Retrieved 2016-02-28.
- ^ “Controlled Drugs and Substances Act (S.C. 1996, c. 19)”. Justice Laws Website. Government of Canada. 24 November 2023.
- ^ Janssen PA (1960). “VII Nitriles”. Diphenylpropylamines. Synthetic Analgesics. Vol. 1. Pergamon Press. pp. 122–128. LCCN 59-13814.