Mitraphylline, an oxindole derivative, is an active alkaloid in the leaves of the tree Mitragyna speciosa, commonly known as kratom.[1] As a non-narcotic constituent, it also occurs in the bark of Uncaria tomentosa (cat’s claw) along with isomeric alkaloids.[2]
References
- ^ Manda, Vamshi; Avula, Bharathi; Ali, Zulfiqar; Khan, Ikhlas; Walker, Larry; Khan, Shabana (May 2014). “Evaluation of In Vitro Absorption, Distribution, Metabolism, and Excretion (ADME) Properties of Mitragynine, 7-Hydroxymitragynine, and Mitraphylline”. Planta Medica. 80 (7): 568–576. Bibcode:2014PlMed..80..568M. doi:10.1055/s-0034-1368444. ISSN 0032-0943. PMID 24841968.
- ^ Stuppner, H.; Sturm, S.; Konwalinka, G. (December 1992). “HPLC analysis of the main oxindole alkaloids from Uncaria tomentosa“. Chromatographia. 34 (11–12): 597–600. doi:10.1007/BF02269869. ISSN 0009-5893. S2CID 95048480.