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A muscle is a contractile tissue in an animal’s body used especially for movement composed of muscle or muscle tissue. In this sense it can refer to:

• Skeletal muscle, the voluntary muscle allowing conscious movement in vertebrates
• Smooth muscle, the muscle of the internal organs of vertebrates, and throughout many invertebrates
• Cardiac muscle, the specialized muscle of the heart

Muscle or Muscles or variation, may also refer to:

• Muscle (TV series), comedy set inside a fictional gym in New York City
• Muscle (film), a 2020 British thriller
• “Muscles”, an episode of the animated TV series Aqua TV Show Show
• Muscles (musician), Australian electronica musician Chris Copulos
• Les Musclés, a 1990s French band
• Muscles (album) (2007), by hip-hop musician Mele Mel
• “Muscles” (song), by Diana Ross
• M.U.S.C.L.E., small pink action figures originally known as Kinkeshi in Japan
• M.U.S.C.L.E. (video game), NES wrestling game based on the manga and anime Kinnikuman
• Mr. Muscles, a superhero in two 1956 comic book issues
• Mister Muscle, a member of the DC Comics Hero Hotline team
• Masked Muscle, an opponent in the Super NES video game Super Punch-Out!!

• “Muscles”, nickname of Venkatapathy Raju (born 1969), Indian former cricketer
• “Muscles”, nickname of Ken Rosewall (born 1934), Australian retired tennis player
• Leo “Muscle” Shoals (1916-1999), American minor league baseball player
• Max Muscle (1963-2019), former American professional wrestler

• ST Muscle a tugboat in service with the French Government from 1946 to 1951
• MUSCLE (alignment software), a multiple sequence alignment tool
• MUSCLE, non-Windows API to Common Access Cards

• All pages with titles beginning with Muscle
• All pages with titles containing Muscle
• Jean-Claude Van Damme (born 1960), Belgian actor and martial artist nicknamed “the Muscles from Brussels”
• Mussel, marine or freshwater species, members of several different families of clams or bivalve molluscs
• Musele (disambiguation)