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PARGY-LAD, also known as 6-propynyl-6-nor-LSD or 6-propargyl-6-nor-LSD, is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD).[3]

Use and effects

PARGY-LAD is hallucinogenic similarly to LSD, but is considerably less potent than LSD, with a dose of 160 μg producing only mild effects, and 500 μg required for full activity.[1]

Interactions

See also: Psychedelic drug § Interactions, and Trip killer § Serotonergic psychedelic antidotes

Chemistry

Analogues

Analogues of PARGY-LAD include LSD, ETH-LAD, PRO-LAD, AL-LAD, BU-LAD, and MAL-LAD, among others.

History

PARGY-LAD was developed by David E. Nichols and colleagues at Purdue University in the 1980s[3] and is described by Alexander Shulgin in his 1997 book TiHKAL (Tryptamines I Have Known and Loved).[1]

See also

References

  1. ^ a b c “#51. PRO-LAD”.Shulgin A, Shulgin A (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN 0-9630096-9-9. OCLC 38503252.
  2. ^ “Arrêté du 20 mai 2021 modifiant l’arrêté du 22 février 1990 fixant la liste des substances classées comme stupéfiants”. www.legifrance.gouv.fr (in French). 20 May 2021.
  3. ^ a b Nichols DE, Oberlender R, McKenna DJ (1991). “Stereochemical Aspects of Hallucinogenesis”. In Watson RR (ed.). Biochemistry and Physiology of Substance Abuse. Vol. 3. Boca Raton, Fla.: CRC Press. pp. 1–39. ISBN 978-0-8493-4463-3. OCLC 26748320. TABLE 1 Effects of N-(6)-Alkyl Subtituents on LSD-Like Behavior and Serotonin Receptor Affinity in Rats […]