Protein arginine N-methyltransferase 3 is an enzyme that in humans is encoded by the PRMT3 gene.[5][6]
Interactions
PRMT3 has been shown to interact with RPS2.[7]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000185238 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030505 – Ensembl, May 2017
- ^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Tang J, Gary JD, Clarke S, Herschman HR (July 1998). “PRMT 3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation”. The Journal of Biological Chemistry. 273 (27): 16935–45. doi:10.1074/jbc.273.27.16935. PMID 9642256.
- ^ “Entrez Gene: PRMT3 protein arginine methyltransferase 3”.
- ^ Choi S, Jung CR, Kim JY, Im DS (September 2008). “PRMT3 inhibits ubiquitination of ribosomal protein S2 and together forms an active enzyme complex”. Biochimica et Biophysica Acta (BBA) – General Subjects. 1780 (9): 1062–9. doi:10.1016/j.bbagen.2008.05.010. PMID 18573314.
Further reading
- Singh V, Miranda TB, Jiang W, Frankel A, Roemer ME, Robb VA, et al. (October 2004). “DAL-1/4.1B tumor suppressor interacts with protein arginine N-methyltransferase 3 (PRMT3) and inhibits its ability to methylate substrates in vitro and in vivo”. Oncogene. 23 (47): 7761–71. doi:10.1038/sj.onc.1208057. PMID 15334060.
- Bachand F, Silver PA (July 2004). “PRMT3 is a ribosomal protein methyltransferase that affects the cellular levels of ribosomal subunits”. The EMBO Journal. 23 (13): 2641–50. doi:10.1038/sj.emboj.7600265. PMC 449775. PMID 15175657.
- Smith JJ, Rücknagel KP, Schierhorn A, Tang J, Nemeth A, Linder M, et al. (May 1999). “Unusual sites of arginine methylation in Poly(A)-binding protein II and in vitro methylation by protein arginine methyltransferases PRMT1 and PRMT3”. The Journal of Biological Chemistry. 274 (19): 13229–34. doi:10.1074/jbc.274.19.13229. PMID 10224081.
External links
- PRMT3 human gene location in the UCSC Genome Browser.
- PRMT3 human gene details in the UCSC Genome Browser.
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