Percavirus is a genus of viruses in the order Herpesvirales, in the family Orthoherpesviridae, in the subfamily Gammaherpesvirinae. Mammals serve as natural hosts. Diseases associated with this genus include: conjunctivitis, immunosuppression in foals, pneumonia, respiratory disease.[1][2]
Species
The genus contains the following species, listed by scientific name and followed by the common name of the species:[2][3]
- Percavirus equidgamma2, Equine herpesvirus 2
- Percavirus equidgamma5, Equine herpesvirus 5
- Percavirus felidgamma1, Felis catus gammaherpesvirus 1
- Percavirus mustelidgamma1, Mustelid herpesvirus 1
- Percavirus phocidgamma3, Harp seal herpesvirus
- Percavirus rhinolophidgamma1, Rhinolophus gammaherpesvirus 1
- Percavirus vespertilionidgamma1, Bat gammaherpesvirus 8
Structure
Viruses in Percavirus are enveloped, with icosahedral, spherical to pleomorphic, and round geometries, and T=16 symmetry. The diameter is around 150-200 nm. Genomes are linear and non-segmented, around 180kb in length.[1]
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Percavirus | Spherical pleomorphic | T=16 | Enveloped | Linear | Monopartite |
Life cycle
Viral replication is nuclear, and is lysogenic. Entry into the host cell is achieved by attachment of the viral glycoproteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear egress, and budding. Mammals serve as the natural host.[1]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Percavirus | Mammals | B-lymphocytes | Glycoprotiens | Budding | Nucleus | Nucleus | Sex; saliva |
References
- ^ a b c “Viral Zone”. ExPASy. Retrieved 15 June 2015.
- ^ a b “Virus Taxonomy: 2023 Release”. ictv.global. International Committee on Taxonomy of Viruses. 30 October 2024. Retrieved 30 January 2025.
- ^ “Species List: Orthoherpesviridae“. International Committee on Taxonomy of Viruses. Retrieved 5 May 2026.
