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UCB may stand for:

Banking

University of California, Berkeley, in the U.S. state of California
Umwelt-Campus Birkenfeld, a branch of the Trier University of Applied Sciences in the German state of Rhineland-Palatinate
Universidad Central de Bayamón, a private Catholic university in the U.S. territory of Puerto Rico
Universidade Católica de Brasília, a private Catholic university in Brazil
University College of Bahrain, in Saar, Bahrain
University College, Bangor, predecessor to Bangor University, in Wales, United Kingdom
University College of Bangor, a campus of the University of Maine at Augusta, in the U.S. state of Maine
University College Birmingham, in England, United Kingdom
University College at Buckingham, predecessor to University of Buckingham, in England, United Kingdom
University of Colorado Boulder, in the U.S. state of Colorado

UCB (company), a global biopharmaceutical manufacturer
Ulanqab Jining Airport, IATA code UCB
Unconjugated Bilirubin, in clinical biochemistry, the yellow breakdown product of normal heme catabolism
Union of Burkinabé Communists, a political party in Burkina Faso in the 1980s
Unit Control Block, in computing, an area of memory in IBM’s z/OS
United Cricket Board of South Africa, a former name of the governing body of cricket in South Africa
Upper Confidence Bound, a term in the confidence interval method, an AI method used in Monte Carlo tree search & multi-armed bandits